A retrospective review of factors associated with response to phototherapy and PUVA for atopic eczema

K. F. Bedair; R. S. Dawe

doi:10.1111/phpp.12609

A retrospective review of factors associated with response to phototherapy and PUVA for atopic eczema

K. F. Bedair, R. S. Dawe (Lead / Corresponding author)

Population Health and Genomics

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Abstract

There is randomised study evidence that narrowband ultraviolet B (NB-UVB) is effective for eczema. A small controlled study did not detect an efficacy difference between bath 8-MOP PUVA (psoralen drug with the main effects limited to the skin as the drug is 'activated' there by ultraviolet A [UVA] exposure) and NB-UVB. Another small randomised study showed that 5-MOP oral PUVA worked better than medium-dose ultraviolet A1 (UVA1). A systematic review concluded that NB-UVB and ultraviolet A1 were the most effective phototherapies for eczema and pointed out the limited comparative evidence regarding PUVA.

Original language	English
Pages (from-to)	153-156
Number of pages	4
Journal	Photodermatology, Photoimmunology & Photomedicine
Volume	37
Issue number	2
Early online date	23 Sept 2020
DOIs	https://doi.org/10.1111/phpp.12609
Publication status	Published - Mar 2021

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Radiology Nuclear Medicine and imaging
Dermatology

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10.1111/phpp.12609

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abstract = "There is randomised study evidence that narrowband ultraviolet B (NB-UVB) is effective for eczema. A small controlled study did not detect an efficacy difference between bath 8-MOP PUVA (psoralen drug with the main effects limited to the skin as the drug is 'activated' there by ultraviolet A [UVA] exposure) and NB-UVB. Another small randomised study showed that 5-MOP oral PUVA worked better than medium-dose ultraviolet A1 (UVA1). A systematic review concluded that NB-UVB and ultraviolet A1 were the most effective phototherapies for eczema and pointed out the limited comparative evidence regarding PUVA.",

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AB - There is randomised study evidence that narrowband ultraviolet B (NB-UVB) is effective for eczema. A small controlled study did not detect an efficacy difference between bath 8-MOP PUVA (psoralen drug with the main effects limited to the skin as the drug is 'activated' there by ultraviolet A [UVA] exposure) and NB-UVB. Another small randomised study showed that 5-MOP oral PUVA worked better than medium-dose ultraviolet A1 (UVA1). A systematic review concluded that NB-UVB and ultraviolet A1 were the most effective phototherapies for eczema and pointed out the limited comparative evidence regarding PUVA.

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A retrospective review of factors associated with response to phototherapy and PUVA for atopic eczema

Abstract

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