A rnyxobacterial S-motility protein dances with poles

Edgar Huitema, Patrick H. Viollier

    Research output: Contribution to journalReview article

    1 Citation (Scopus)

    Abstract

    Coordinated movement of packs of S-motile Myxococcus xanthus cells relies on extrusion and retraction of pili that are located at one cell pole. At regular intervals the pili switch their polar location and cells reverse direction. Recently, the FrzS S-motility protein was observed to localize predominantly to the piliated pole. In time, FrzS was redeployed to the opposite pole and its sequestration at the new site coincided with cell reversal. The C-terminal region of FrzS, a response regulator homolog, is rich in coiled-coil motifs and is required for dynamic localization and proper motility. These results raise the possibility that proper spatial control of FrzS has an important role in the regulation of cell reversal and S-motility.

    Original languageEnglish
    Pages (from-to)247-248
    Number of pages2
    JournalTrends in Microbiology
    Volume14
    Issue number6
    DOIs
    Publication statusPublished - Jun 2006

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