A Role for Dormant Origins in Tumor Suppression

Kathleen Klotz-Noack, J. Julian Blow

    Research output: Contribution to journalEditorial

    5 Citations (Scopus)

    Abstract

    In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

    Original languageEnglish
    Pages (from-to)495-496
    Number of pages2
    JournalMolecular Cell
    Volume41
    Issue number5
    DOIs
    Publication statusPublished - 4 Mar 2011

    Keywords

    • REPLICATIVE STRESS
    • EXCESS MCM2-7
    • CANCER
    • MICE

    Cite this

    Klotz-Noack, Kathleen ; Blow, J. Julian. / A Role for Dormant Origins in Tumor Suppression. In: Molecular Cell. 2011 ; Vol. 41, No. 5. pp. 495-496.
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    abstract = "In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.",
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    A Role for Dormant Origins in Tumor Suppression. / Klotz-Noack, Kathleen; Blow, J. Julian.

    In: Molecular Cell, Vol. 41, No. 5, 04.03.2011, p. 495-496.

    Research output: Contribution to journalEditorial

    TY - JOUR

    T1 - A Role for Dormant Origins in Tumor Suppression

    AU - Klotz-Noack, Kathleen

    AU - Blow, J. Julian

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    AB - In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

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    KW - EXCESS MCM2-7

    KW - CANCER

    KW - MICE

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    DO - 10.1016/j.molcel.2011.02.014

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    JF - Molecular Cell

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