A Role for Dormant Origins in Tumor Suppression

Kathleen Klotz-Noack; J. Julian Blow

doi:10.1016/j.molcel.2011.02.014

A Role for Dormant Origins in Tumor Suppression

Kathleen Klotz-Noack
, J. Julian Blow

Research output: Contribution to journal › Editorial › peer-review

6 Citations (Scopus)

Abstract

In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

Original language	English
Pages (from-to)	495-496
Number of pages	2
Journal	Molecular Cell
Volume	41
Issue number	5
DOIs	https://doi.org/10.1016/j.molcel.2011.02.014
Publication status	Published - 4 Mar 2011

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

REPLICATIVE STRESS
EXCESS MCM2-7
CANCER
MICE

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10.1016/j.molcel.2011.02.014

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@article{ae394141028742408855f807bbd8355a,

title = "A Role for Dormant Origins in Tumor Suppression",

abstract = "In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.",

keywords = "REPLICATIVE STRESS, EXCESS MCM2-7, CANCER, MICE",

author = "Kathleen Klotz-Noack and Blow, \{J. Julian\}",

year = "2011",

month = mar,

day = "4",

doi = "10.1016/j.molcel.2011.02.014",

language = "English",

volume = "41",

pages = "495--496",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - A Role for Dormant Origins in Tumor Suppression

AU - Klotz-Noack, Kathleen

AU - Blow, J. Julian

PY - 2011/3/4

Y1 - 2011/3/4

N2 - In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

AB - In this issue of Molecular Cell, Kawabata et al. (2011) show that mice hypomorphic for the replication licensing protein Mcm4 show spontaneous DNA replication defects due to a lack of dormant origins, potentially explaining why these mice are cancer prone.

KW - REPLICATIVE STRESS

KW - EXCESS MCM2-7

KW - CANCER

KW - MICE

U2 - 10.1016/j.molcel.2011.02.014

DO - 10.1016/j.molcel.2011.02.014

M3 - Editorial

C2 - 21362544

SN - 1097-2765

VL - 41

SP - 495

EP - 496

JO - Molecular Cell

JF - Molecular Cell

IS - 5

ER -

A Role for Dormant Origins in Tumor Suppression

Abstract

UN SDGs

Keywords

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