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In this research, a silver nanoparticle/polytetrafluorethylene (AgNP/PTFE) coating for metallic implants was fabricated using a facile layer-by-layer coating method. PTFE nanoparticles were immobilized in a sol-gel matrix and dip-coated onto 316L stainless steel via a mussel-inspired approach followed by AgNP deposition. Benefiting from the synergistic effect of antibacterial AgNP and non-stick PTFE, the AgNP/PTFE coating exhibited superior antibiofilm activity against Escherichia coli WT F1693 and enhanced corrosion resistance. Compared with surfaces only coated with PTFE, the AgNP/PTFE coated surfaces were capable of sustained release of silver ions, inhibiting up to ∼50% bacterial biomass accumulation after 7 days. To understand the anti-adhesion mechanism, both classic DLVO and XDLVO theories were used to model and explain bacterial adhesion. Despite concerns that an over-release of silver ions may cause toxic effects towards mammalian cells, the coating procedures offered ease of control over the silver loading, making it potentially useful for preventing metallic implant-associated infections.
|Number of pages||10|
|Journal||Applied Surface Science|
|Early online date||29 Aug 2020|
|Publication status||Published - 1 Jan 2021|
- antibacterial activity
- Antibacterial activity
ASJC Scopus subject areas
- Condensed Matter Physics
- Physics and Astronomy(all)
- Surfaces, Coatings and Films
- Surfaces and Interfaces
FingerprintDive into the research topics of 'A sol-gel based silver nanoparticle/polytetrafluorethylene (AgNP/PTFE) coating with enhanced antibacterial and anti-corrosive properties'. Together they form a unique fingerprint.
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Influence of Surface Properties of New Biomaterials for Catheters on Bacterial Adhesion Urine
Campbell, P., Corner, G., Davidson, F., Keatch, R., Nabi, G., Vorstius, J., Wilcox, K. & Zhao, Q.
Engineering and Physical Sciences Research Council
1/12/16 → 31/10/21