A straightforward total synthesis of (-)-chaetominine

Keyphrases

• Total Synthesis 100%
• Chaetominine 100%
• Diastereoisomers 66%
• Oxaziridines 66%
• Inhibitory Activity 33%
• Acyl 33%
• Quinolones 33%
• Commercially Available 33%
• Indole 33%
• Cancer Cell Lines 33%
• Alkaloids 33%
• Cyclization 33%
• Overall Yield 33%
• Methyl Ester 33%
• Synthetic Strategies 33%
• Tripeptide 33%
• Sequence of Steps 33%
• Double Bond 33%
• Hydroxy Group 33%
• Struction 33%
• Et3SiH 33%
• Protective Group 33%
• N-Acyliminium Ion 33%
• D-ring 33%
• Tetracyclic 33%
• Indole Ring 33%
• Pyrido 33%
• Stereocontrol 33%

Chemistry

• Chaetominine 100%
• Indole 66%
• Oxaziridine 66%
• Hydroxyl Group 33%
• Protective 33%
• Methyl Ester 33%
• Double Bond 33%
• Tripeptide 33%