A systematic review of the cost-effectiveness of non-surgical obesity interventions in men

Dwayne Boyers (Lead / Corresponding author), Alison Avenell, Fiona Stewart, Clare Robertson, Daryll Archibald, Flora Douglas, Pat Hoddinott, Edwin van Teijlingen

    Research output: Contribution to journalReview articlepeer-review

    8 Citations (Scopus)


    Background Increasing obesity related health conditions have a substantial burden on population health and healthcare spending. Obesity may have a sex-specific impact on disease development, men and women may respond differently to interventions, and there may be sex-specific differences to the cost-effectiveness of interventions to address obesity. There is no clear indication of cost-effective treatments for men. 

    Methods This systematic review summarises the literature reporting the cost-effectiveness of non-surgical weight-management interventions for men. Studies were quality assessed against a checklist for appraising decision modelling studies. 

    Results Although none of the included studies explicitly set out to determine the cost-effectiveness of treatment for men, seven studies reported results for subgroups of men. Interventions were grouped into lifestyle interventions (five studies) and Orlistat (two studies). The retrieved studies showed promising evidence of cost-effectiveness, especially when interventions were targeted at high-risk groups, such as those with impaired glucose tolerance. There appears to be some sex-specific elements to cost-effectiveness, however, there were no clear trends or indications of what may be contributing to this. 

    Conclusion The economic evidence was highly uncertain, and limited by variable methodological quality of the included studies. It was therefore not possible to draw strong conclusions on cost-effectiveness. Future studies are required to demonstrate the cost-effectiveness of interventions specifically targeted towards weight loss for men.

    Original languageEnglish
    Pages (from-to)310-327
    Number of pages18
    JournalObesity Research and Clinical Practice
    Issue number4
    Early online date1 Apr 2015
    Publication statusPublished - Jul 2015


    • Cost-effectiveness
    • Decision analysis
    • Men's health
    • Obesity treatment

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Nutrition and Dietetics


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