A unified classification system for eukaryotic transposable elements

Thomas Wicker, Francois Sabot, Aurelie Hua-Van, Jeffrey L. Bennetzen, Pierre Capy, Boulos Chalhoub, Andrew Flavell, Philippe Leroy, Michele Morgante, Olivier Panaud, Etienne Paux, Phillip SanMiguel, Alan H. Schulman

    Research output: Contribution to journalReview articlepeer-review

    1347 Citations (Scopus)

    Abstract

    Our knowledge of the structure and composition of genomes is rapidly progressing in pace with their sequencing. The emerging data show that a significant portion of eukaryotic genomes is composed of transposable elements (TEs). Given the abundance and diversity of TEs and the speed at which large quantities of sequence data are emerging, identification and annotation of TEs presents a significant challenge. Here we propose the first unified hierarchical classification system, designed on the basis of the transposition mechanism, sequence similarities and structural relationships, that can be easily applied by non-experts. The system and nomenclature is kept up to date at the WikiPoson web site.

    Original languageEnglish
    Pages (from-to)973-982
    Number of pages10
    JournalNature Reviews Genetics
    Volume8
    Issue number12
    DOIs
    Publication statusPublished - Dec 2007

    Keywords

    • ROLLING-CIRCLE TRANSPOSONS
    • NON-LTR RETROTRANSPOSONS
    • DNA TRANSPOSONS
    • DROSOPHILA-MELANOGASTER
    • INTERGENE RETROTRANSPOSONS
    • MASSIVE AMPLIFICATION
    • EVOLUTIONARY DYNAMICS
    • REPETITIVE ELEMENTS
    • GENOME EVOLUTION
    • TERMINAL REPEATS

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