A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Pedro Jares; M. Gloria Luciani; J. Julian Blow

doi:10.1186/1471-2199-5-5

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Pedro Jares, M. Gloria Luciani, J. Julian Blow

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24 Citations (Scopus)

Abstract

Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin Recognition Complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins onto chromatin to license the origin for use in the subsequent S phase. Licensed origins must then be activated by S phase-inducing cyclin-dependent kinases (S-CDKs) and the Dbf4/Cdc7 kinase.

Original language	English
Article number	5
Pages (from-to)	1-14
Number of pages	14
Journal	BMC Molecular Biology
Volume	5
DOIs	https://doi.org/10.1186/1471-2199-5-5
Publication status	Published - 2004

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title = "A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication",

abstract = "Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin Recognition Complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins onto chromatin to license the origin for use in the subsequent S phase. Licensed origins must then be activated by S phase-inducing cyclin-dependent kinases (S-CDKs) and the Dbf4/Cdc7 kinase.",

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year = "2004",

doi = "10.1186/1471-2199-5-5",

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T1 - A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

AU - Jares, Pedro

AU - Luciani, M. Gloria

AU - Blow, J. Julian

PY - 2004

Y1 - 2004

N2 - Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin Recognition Complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins onto chromatin to license the origin for use in the subsequent S phase. Licensed origins must then be activated by S phase-inducing cyclin-dependent kinases (S-CDKs) and the Dbf4/Cdc7 kinase.

AB - Early in the cell cycle a pre-replicative complex (pre-RC) is assembled at each replication origin. This process involves the sequential assembly of the Origin Recognition Complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins onto chromatin to license the origin for use in the subsequent S phase. Licensed origins must then be activated by S phase-inducing cyclin-dependent kinases (S-CDKs) and the Dbf4/Cdc7 kinase.

U2 - 10.1186/1471-2199-5-5

DO - 10.1186/1471-2199-5-5

M3 - Article

C2 - 15222894

VL - 5

SP - 1

EP - 14

JO - BMC Molecular Biology

JF - BMC Molecular Biology

M1 - 5

ER -

A Xenopus Dbf4 homolog is required for Cdc7 chromatin binding and DNA replication

Abstract

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