Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol

David G Kiely; Robert I Cargill; Alison Grove; Allan D Struthers; Brian J Lipworth

doi:10.1136/thx.50.10.1062

Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol

David G Kiely
, Robert I Cargill
, Alison Grove
, Allan D Struthers
, Brian J Lipworth

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Prolongation of the QTc interval has been associated with cardiac dysrhythmias and sudden death. QTc dispersion (interlead variability in QTc interval) has recently been proposed as being a more sensitive marker of repolarisation abnormalities and shown to be a more specific index of arrhythmia risk. Although hypoxaemia and fenoterol have previously been shown to prolong the QTc interval, this does not reflect regional myocardial repolarisation abnormalities.

Original language	English
Pages (from-to)	1062-6
Number of pages	5
Journal	Thorax
Volume	50
Issue number	10
DOIs	https://doi.org/10.1136/thx.50.10.1062
Publication status	Published - Oct 1995

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title = "Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol",

abstract = "Prolongation of the QTc interval has been associated with cardiac dysrhythmias and sudden death. QTc dispersion (interlead variability in QTc interval) has recently been proposed as being a more sensitive marker of repolarisation abnormalities and shown to be a more specific index of arrhythmia risk. Although hypoxaemia and fenoterol have previously been shown to prolong the QTc interval, this does not reflect regional myocardial repolarisation abnormalities.",

author = "Kiely, \{David G\} and Cargill, \{Robert I\} and Alison Grove and Struthers, \{Allan D\} and Lipworth, \{Brian J\}",

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T1 - Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol

AU - Kiely, David G

AU - Cargill, Robert I

AU - Grove, Alison

AU - Struthers, Allan D

AU - Lipworth, Brian J

PY - 1995/10

Y1 - 1995/10

N2 - Prolongation of the QTc interval has been associated with cardiac dysrhythmias and sudden death. QTc dispersion (interlead variability in QTc interval) has recently been proposed as being a more sensitive marker of repolarisation abnormalities and shown to be a more specific index of arrhythmia risk. Although hypoxaemia and fenoterol have previously been shown to prolong the QTc interval, this does not reflect regional myocardial repolarisation abnormalities.

AB - Prolongation of the QTc interval has been associated with cardiac dysrhythmias and sudden death. QTc dispersion (interlead variability in QTc interval) has recently been proposed as being a more sensitive marker of repolarisation abnormalities and shown to be a more specific index of arrhythmia risk. Although hypoxaemia and fenoterol have previously been shown to prolong the QTc interval, this does not reflect regional myocardial repolarisation abnormalities.

U2 - 10.1136/thx.50.10.1062

DO - 10.1136/thx.50.10.1062

M3 - Article

C2 - 7491554

SN - 0040-6376

VL - 50

SP - 1062

EP - 1066

JO - Thorax

JF - Thorax

IS - 10

ER -

Abnormal myocardial repolarisation in response to hypoxaemia and fenoterol

Abstract

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