Acceptor analogues as potential inhibitors of bovine β-1,4-galactosyl transferase

Robert A. Field, David C. A. Neville, Roland W. Smith, Michael A. J. Ferguson

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    A series of 4- and 6-substituted derivatives of benzyl N-acetyl-ß-D- glucosaminide were prepared and assessed as inhibitors of bovine ß-1,4- galactosyl transferase. Of the azido, amino, and acetamido compounds tested, only the 4-amino compound (2) produced significant inhibition of this enzyme.
    Original languageEnglish
    Pages (from-to)391-394
    Number of pages4
    JournalBioorganic & Medicinal Chemistry Letters
    Volume4
    Issue number3
    DOIs
    Publication statusPublished - 1 Jan 1994

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