Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo

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11 Citations (Scopus)

Abstract

Activation of mGluRs has previously been reported to cause beta/gamma frequency oscillations in CA1 hippocampal slices. The present study reveals that pharmacological activation of mGluRs in vivo induces dentate EEG oscillations at the low end of the gamma frequency range, with peak activity just below 30 Hz.

Original languageEnglish
Pages (from-to)634-7
Number of pages4
JournalNeuropharmacology
Volume40
Issue number4
Publication statusPublished - Mar 2001

Keywords

  • Animals
  • Benzoates/pharmacology
  • Cycloleucine/analogs & derivatives
  • Dentate Gyrus/drug effects
  • Electroencephalography
  • Excitatory Amino Acid Antagonists/pharmacology
  • Glycine/analogs & derivatives
  • Male
  • Rats
  • Receptors, Metabotropic Glutamate/agonists
  • Time Factors

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