Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe

Eileen Furlong (Lead / Corresponding author), Andrew Darley, Patricia Fox, Alison Buick, Grigorios Kotronoulas, Morven Miller, Adrian Flowerday, Christine Miaskowski, Elisabeth Patiraki, Stylianos Katsaragakis, Emma Ream, Jo Armes, Alexander Gaiger, Geir Berg, Paul McCrone, Peter Donnan, Lisa McCann, Roma Maguire

Research output: Contribution to journalArticle

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Abstract

Background: There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings.

Objective: This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone-based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care.

Methods: There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center.

Results: The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT.

Conclusions: Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.

Original languageEnglish
Article numbere10813
Pages (from-to)1-14
Number of pages14
JournalJMIR Cancer
Volume5
Issue number1
DOIs
Publication statusPublished - 14 Mar 2019

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Cell Phones
Communication
Technology
Neoplasms
Randomized Controlled Trials
Austria
Validation Studies
Greece
Norway
Adjuvant Chemotherapy
Linguistics
Ireland
Industry
Guidelines
Delivery of Health Care
Drug Therapy
Health
Research

Keywords

  • Cancer
  • Methods
  • Patient care
  • Symptom management
  • Telemedicine

Cite this

Furlong, E., Darley, A., Fox, P., Buick, A., Kotronoulas, G., Miller, M., ... Maguire, R. (2019). Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe. JMIR Cancer, 5(1), 1-14. [e10813]. https://doi.org/10.2196/10813
Furlong, Eileen ; Darley, Andrew ; Fox, Patricia ; Buick, Alison ; Kotronoulas, Grigorios ; Miller, Morven ; Flowerday, Adrian ; Miaskowski, Christine ; Patiraki, Elisabeth ; Katsaragakis, Stylianos ; Ream, Emma ; Armes, Jo ; Gaiger, Alexander ; Berg, Geir ; McCrone, Paul ; Donnan, Peter ; McCann, Lisa ; Maguire, Roma. / Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe. In: JMIR Cancer. 2019 ; Vol. 5, No. 1. pp. 1-14.
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abstract = "Background: There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings.Objective: This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone-based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care.Methods: There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center.Results: The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT.Conclusions: Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.",
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Furlong, E, Darley, A, Fox, P, Buick, A, Kotronoulas, G, Miller, M, Flowerday, A, Miaskowski, C, Patiraki, E, Katsaragakis, S, Ream, E, Armes, J, Gaiger, A, Berg, G, McCrone, P, Donnan, P, McCann, L & Maguire, R 2019, 'Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe', JMIR Cancer, vol. 5, no. 1, e10813, pp. 1-14. https://doi.org/10.2196/10813

Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe. / Furlong, Eileen (Lead / Corresponding author); Darley, Andrew; Fox, Patricia; Buick, Alison; Kotronoulas, Grigorios; Miller, Morven; Flowerday, Adrian; Miaskowski, Christine; Patiraki, Elisabeth; Katsaragakis, Stylianos; Ream, Emma; Armes, Jo; Gaiger, Alexander; Berg, Geir; McCrone, Paul; Donnan, Peter; McCann, Lisa; Maguire, Roma.

In: JMIR Cancer, Vol. 5, No. 1, e10813, 14.03.2019, p. 1-14.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Adaptation and Implementation of a Mobile Phone-Based Remote Symptom Monitoring System for People With Cancer in Europe

AU - Furlong, Eileen

AU - Darley, Andrew

AU - Fox, Patricia

AU - Buick, Alison

AU - Kotronoulas, Grigorios

AU - Miller, Morven

AU - Flowerday, Adrian

AU - Miaskowski, Christine

AU - Patiraki, Elisabeth

AU - Katsaragakis, Stylianos

AU - Ream, Emma

AU - Armes, Jo

AU - Gaiger, Alexander

AU - Berg, Geir

AU - McCrone, Paul

AU - Donnan, Peter

AU - McCann, Lisa

AU - Maguire, Roma

N1 - This project received funding from the European Union’s Seventh Framework Programme for research, technological development, and demonstration under grant agreement number 602289. PD has received grants from Shire Pharmaceuticals and Gilead Sciences

PY - 2019/3/14

Y1 - 2019/3/14

N2 - Background: There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings.Objective: This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone-based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care.Methods: There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center.Results: The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT.Conclusions: Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.

AB - Background: There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and implementing technology of this kind across multiple countries and clinical settings.Objective: This study aimed to describe the steps undertaken in the preparation of a multinational, multicenter randomized controlled trial (RCT) to test a mobile phone-based remote symptom monitoring system, that is, Advanced Symptom Management System (ASyMS), designed to enhance management of chemotherapy toxicities among people with cancer receiving adjuvant chemotherapy versus standard cancer center care.Methods: There were 13 cancer centers across 5 European countries (Austria, Greece, Ireland, Norway, and the United Kingdom). Multiple steps were undertaken, including a scoping review of empirical literature and clinical guidelines, translation and linguistic validation of study materials, development of standardized international care procedures, and the integration and evaluation of the technology within each cancer center.Results: The ASyMS was successfully implemented and deployed in clinical practices across 5 European countries. The rigorous and simultaneous steps undertaken by the research team highlighted the strengths of the system in clinical practice, as well as the clinical and technical changes required to meet the diverse needs of its intended users within each country, before the commencement of the RCT.Conclusions: Adapting and implementing this multinational, multicenter system required close attention to diverse considerations and unique challenges primarily related to communication and clinical and technical issues. Success was dependent on collaborative and transparent communication among academics, the technology industry, translation partners, patients, and clinicians as well as a simultaneous and rigorous methodological approach within the 5 relevant countries.

KW - Cancer

KW - Methods

KW - Patient care

KW - Symptom management

KW - Telemedicine

U2 - 10.2196/10813

DO - 10.2196/10813

M3 - Article

VL - 5

SP - 1

EP - 14

JO - JMIR Cancer

JF - JMIR Cancer

SN - 2369-1999

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