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Abstract
Bacterial infection and corrosion are two of the most common causes of the failure for the use of biomedical metallic implants. In this paper, we developed a facile two-step approach for synthesizing a TiO2-PTFE nanocomposite coating on stainless steel substrate with both antibacterial and anticorrosion properties by using a sol-gel dip coating technique. A sub-layer of bioinspired polydopamine (PDA) was first coated on the stainless steel substrate to improve the adhesion and reactivity, then TiO2-PTFE was uniformly co-deposited onto the PDA sub-layer. Both PTFE and TiO2 contents had a significant influence on the surface energy of the TiO2-PTFE coating. The coating with the total surface energy of 26 mJ/m2 exhibited minimal bacterial adhesion against both Gram-negative Escherichia coli WT F1693 and Gram-positive Staphylococcus aureus F1557, which was explained using the extended DLVO theory. Benefiting from the synergistic effect between TiO2 and PTFE, the TiO2-PTFE coating showed improved corrosion resistance in artificial body fluids compared with the sole TiO2 coating or PTFE coating. The TiO2-PTFE coating also demonstrated extraordinary biocompatibility with fibroblast cells in culture, making it a prospective strategy to overcome current challenges in the use of metallic implants.
Original language | English |
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Pages (from-to) | 231-241 |
Number of pages | 11 |
Journal | Applied Surface Science |
Volume | 490 |
Early online date | 8 Jun 2019 |
DOIs | |
Publication status | Published - 1 Oct 2019 |
Keywords
- Titanium dioxide
- Polytetrafluoroethylene
- Surface energy
- Antibacterial activity
- Corrosion
Fingerprint
Dive into the research topics of 'Advanced titanium dioxide-polytetrafluorethylene (TiO2-PTFE) nanocomposite coatings on stainless steel surfaces with antibacterial and anti-corrosion properties'. Together they form a unique fingerprint.Projects
- 1 Finished
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Influence of Surface Properties of New Biomaterials for Catheters on Bacterial Adhesion Urine
Campbell, P., Corner, G., Davidson, F., Keatch, R., Nabi, G., Vorstius, J., Wilcox, K. & Zhao, Q.
Engineering and Physical Sciences Research Council
1/12/16 → 31/10/21
Project: Research
Profiles
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Zhao, Qi
- Mechanical and Electronic Engineering - Professor & Materials Science and Engineering
Person: Academic