Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast

Jeremy Thomas (Lead / Corresponding author), Andrew Hanby, Sarah E. Pinder, Graham Ball, Gill Lawrence, Anthony Maxwell, Mathew Wallis, Andrew Evans, Hilary Dobson, Karen Clements, Alastair Thompson, Sloane Project Steering Group

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    Abstract

    Background: The Sloane Project is the largest prospective audit of ductal carcinoma in situ (DCIS) worldwide, with over 12,000 patients registered between 2003 and 2012, accounting for 50% of screen-detected DCIS diagnosed in the United Kingdom (UK) over the period of accrual. Methods: Complete multidisciplinary data from 8313 patients with screen-detected DCIS were analysed for surgical outcome in relation to key radiological and pathological parameters for the cohort and also by hospital of treatment. Adverse surgical outcomes were defined as either failed breast conservation surgery (BCS) or mastectomy for small lesions (
    Original languageEnglish
    Pages (from-to)1880-1890
    Number of pages11
    JournalEuropean Journal of Cancer
    Volume50
    Issue number11
    DOIs
    Publication statusPublished - Jul 2014

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    Thomas, J., Hanby, A., Pinder, S. E., Ball, G., Lawrence, G., Maxwell, A., Wallis, M., Evans, A., Dobson, H., Clements, K., Thompson, A., & Sloane Project Steering Group (2014). Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast. European Journal of Cancer, 50(11), 1880-1890. https://doi.org/10.1016/j.ejca.2014.02.023