Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease

the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators; Jeffrey T. J. Huang; Charlotte E. Bolton; Bruce E. Miller; Ruth Tal-Singer; Roberto A. Rabinovich; Colin N. A. Palmer; Neil C. Thomson; William MacNee

doi:10.1183/13993003.01125-2016

Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease

the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators, Jeffrey T. J. Huang (Lead / Corresponding author), Charlotte E. Bolton, Bruce E. Miller, Ruth Tal-Singer, Roberto A. Rabinovich, Colin N. A. Palmer, Neil C. Thomson, William MacNee

Research output: Contribution to journal › Letter › peer-review

26 Citations (Scopus)

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Abstract

Elastin turnover increases with chronological age and COPD accelerates this process beyond normal ageing.

Original language	English
Pages (from-to)	1215-1218
Number of pages	4
Journal	European Respiratory Journal
Volume	48
Issue number	4
Early online date	1 Sept 2016
DOIs	https://doi.org/10.1183/13993003.01125-2016
Publication status	Published - 30 Sept 2016

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Author Accepted ManuscriptAccepted author manuscript, 623 KB

Huang, Jeffrey
- Respiratory Medicine and Gastroenterology - Principal Investigator/Senior Lecturer (Tenure Track)
- Biomarker and Drug Analysis Laboratory
Person: Academic Related, Academic

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the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators, Huang, J. T. J., Bolton, C. E., Miller, B. E., Tal-Singer, R., Rabinovich, R. A., Palmer, C. N. A., Thomson, N. C., & MacNee, W. (2016). Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease. European Respiratory Journal, 48(4), 1215-1218. https://doi.org/10.1183/13993003.01125-2016

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title = "Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease",

abstract = "Elastin turnover increases with chronological age and COPD accelerates this process beyond normal ageing. ",

author = "{the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators} and Huang, {Jeffrey T. J.} and Bolton, {Charlotte E.} and Miller, {Bruce E.} and Ruth Tal-Singer and Rabinovich, {Roberto A.} and Palmer, {Colin N. A.} and Thomson, {Neil C.} and William MacNee",

note = "GlaxoSmithKline NCT00292552, GSK Study No. SCO104960",

year = "2016",

month = sep,

day = "30",

doi = "10.1183/13993003.01125-2016",

language = "English",

volume = "48",

pages = "1215--1218",

journal = "European Respiratory Journal",

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the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators, Huang, JTJ, Bolton, CE, Miller, BE, Tal-Singer, R, Rabinovich, RA, Palmer, CNA, Thomson, NC & MacNee, W 2016, 'Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease', European Respiratory Journal, vol. 48, no. 4, pp. 1215-1218. https://doi.org/10.1183/13993003.01125-2016

Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease. / the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators ; Huang, Jeffrey T. J. (Lead / Corresponding author); Bolton, Charlotte E. et al.
In: European Respiratory Journal, Vol. 48, No. 4, 30.09.2016, p. 1215-1218.

Research output: Contribution to journal › Letter › peer-review

TY - JOUR

T1 - Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease

AU - the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators

AU - Huang, Jeffrey T. J.

AU - Bolton, Charlotte E.

AU - Miller, Bruce E.

AU - Tal-Singer, Ruth

AU - Rabinovich, Roberto A.

AU - Palmer, Colin N. A.

AU - Thomson, Neil C.

AU - MacNee, William

N1 - GlaxoSmithKline NCT00292552, GSK Study No. SCO104960

PY - 2016/9/30

Y1 - 2016/9/30

N2 - Elastin turnover increases with chronological age and COPD accelerates this process beyond normal ageing.

AB - Elastin turnover increases with chronological age and COPD accelerates this process beyond normal ageing.

U2 - 10.1183/13993003.01125-2016

DO - 10.1183/13993003.01125-2016

M3 - Letter

C2 - 27587547

SN - 0903-1936

VL - 48

SP - 1215

EP - 1218

JO - European Respiratory Journal

JF - European Respiratory Journal

IS - 4

ER -

the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators, Huang JTJ, Bolton CE, Miller BE, Tal-Singer R, Rabinovich RA et al. Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease. European Respiratory Journal. 2016 Sept 30;48(4):1215-1218. Epub 2016 Sept 1. doi: 10.1183/13993003.01125-2016

Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease

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Huang, Jeffrey

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