Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients

Robert J. MacFadyen, Craig S. Barr, Allan D. Struthers

    Research output: Contribution to journalArticle

    314 Citations (Scopus)

    Abstract

    Experimental data suggest that aldosterone has harmful effects promoting myocardial fibrosis and disturbing autonomic balance. There has been no evidence of these potential effects in intact man.
    Original languageEnglish
    Pages (from-to)30-4
    Number of pages5
    JournalCardiovascular Research
    Volume35
    Issue number1
    DOIs
    Publication statusPublished - Jul 1997

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