Alignment-free design of highly discriminatory diagnostic primer sets for Escherichia coli O104: H4 outbreak strains

Keyphrases

• Primer Set 100%
• Diagnostic Primers 100%
• Escherichia Coli O104 100%
• Alignment-free 100%
• Outbreak Strains 100%
• Escherichia Coli 50%
• High-throughput 33%
• High-throughput Sequencing 33%
• Disease Outbreaks 33%
• Primer Design 33%
• Non-breakup 33%
• Epidemiology 16%
• Germany 16%
• Europe 16%
• Societal Impacts 16%
• Rapid Response 16%
• False Positive Rate 16%
• Genome Sequencing 16%
• PCR Primers 16%
• Bacterial Origin 16%
• Draft Genome Sequence 16%
• Diagnostic Performance 16%
• Economic Impact 16%
• Clinical Diagnostics 16%
• Public Database 16%
• Extraintestinal Pathogenic E. Coli (ExPEC) 16%
• Molecular Assay 16%
• Social Impact 16%
• Genome Analysis 16%
• Crowdsourcing 16%
• Bacterial Genomes 16%
• Design Strategy 16%
• Technology Data 16%
• Negative Sequence 16%
• Diagnostic PCR 16%
• Outbreak Investigation 16%
• Draft Genome 16%
• Sequence Set 16%
• Plasmid Sequence 16%
• Atypical Hemolytic Uremic Syndrome (aHUS) 16%
• Disease Threat 16%
• Crowdsourced Data 16%
• Political Impact 16%
• O104 16%
• Genome Assembly 16%
• Genome Diagnostics 16%

Biochemistry, Genetics and Molecular Biology

• Escherichia coli 100%
• Escherichia Coli O104:H4 100%
• High Throughput Sequencing 28%
• Plasmid 14%
• Serotype 14%
• Bacterial Genome 14%
• Pathogenic Escherichia Coli 14%
• Genome Sequencing 14%