All-optical dual photoacoustic and optical coherence tomography intravascular probe

Sunish J. Mathews; Callum Little; Christopher D. Loder; Roby D. Rakhit; Wenfeng Xia; Edward Z. Zhang; Paul C. Beard; Malcolm C. Finlay; Adrien E. Desjardins

doi:10.1016/j.pacs.2018.07.002

All-optical dual photoacoustic and optical coherence tomography intravascular probe

Sunish J. Mathews (Lead / Corresponding author)
, Callum Little
, Christopher D. Loder
, Roby D. Rakhit
, Wenfeng Xia
, Edward Z. Zhang
, Paul C. Beard
, Malcolm C. Finlay
, Adrien E. Desjardins

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Intravascular imaging in percutaneous coronary interventions can be an invaluable tool in the treatment of coronary artery disease. It is of significant interest to provide molecular imaging contrast that is complementary to structural contrast provided by optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS). In this study, we developed a dual-modality intravascular imaging probe comprising a commercial OCT catheter and a high sensitivity fiber optic ultrasound sensor, to provide both photoacoustic (PA) and OCT imaging. With PA imaging, the lateral resolution varied from 18μmto40μm; the axial resolution was consistently in the vicinity of 45 μm. We demonstrated the clinical potential of the probe with 2-D circumferential PA and OCT imaging, and with multispectral PA imaging.

Original language	English
Pages (from-to)	65 - 70
Number of pages	6
Journal	Photoacoustics
Volume	11
Early online date	24 Jul 2018
DOIs	https://doi.org/10.1016/j.pacs.2018.07.002
Publication status	Published - 14 Aug 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Endoscopic imaging
Intravascular photoacoustic imaging
Optical coherence tomography
All-optical intravascular catheter
Fiber optic ultrasound sensor

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10.1016/j.pacs.2018.07.002

Cite this

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title = "All-optical dual photoacoustic and optical coherence tomography intravascular probe",

abstract = "Intravascular imaging in percutaneous coronary interventions can be an invaluable tool in the treatment of coronary artery disease. It is of significant interest to provide molecular imaging contrast that is complementary to structural contrast provided by optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS). In this study, we developed a dual-modality intravascular imaging probe comprising a commercial OCT catheter and a high sensitivity fiber optic ultrasound sensor, to provide both photoacoustic (PA) and OCT imaging. With PA imaging, the lateral resolution varied from 18μmto40μm; the axial resolution was consistently in the vicinity of 45 μm. We demonstrated the clinical potential of the probe with 2-D circumferential PA and OCT imaging, and with multispectral PA imaging.",

keywords = "Endoscopic imaging, Intravascular photoacoustic imaging, Optical coherence tomography, All-optical intravascular catheter, Fiber optic ultrasound sensor",

author = "Mathews, \{Sunish J.\} and Callum Little and Loder, \{Christopher D.\} and Rakhit, \{Roby D.\} and Wenfeng Xia and Zhang, \{Edward Z.\} and Beard, \{Paul C.\} and Finlay, \{Malcolm C.\} and Desjardins, \{Adrien E.\}",

year = "2018",

month = aug,

day = "14",

doi = "10.1016/j.pacs.2018.07.002",

language = "English",

volume = "11",

pages = "65 -- 70",

journal = "Photoacoustics",

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}

TY - JOUR

T1 - All-optical dual photoacoustic and optical coherence tomography intravascular probe

AU - Mathews, Sunish J.

AU - Little, Callum

AU - Loder, Christopher D.

AU - Rakhit, Roby D.

AU - Xia, Wenfeng

AU - Zhang, Edward Z.

AU - Beard, Paul C.

AU - Finlay, Malcolm C.

AU - Desjardins, Adrien E.

PY - 2018/8/14

Y1 - 2018/8/14

N2 - Intravascular imaging in percutaneous coronary interventions can be an invaluable tool in the treatment of coronary artery disease. It is of significant interest to provide molecular imaging contrast that is complementary to structural contrast provided by optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS). In this study, we developed a dual-modality intravascular imaging probe comprising a commercial OCT catheter and a high sensitivity fiber optic ultrasound sensor, to provide both photoacoustic (PA) and OCT imaging. With PA imaging, the lateral resolution varied from 18μmto40μm; the axial resolution was consistently in the vicinity of 45 μm. We demonstrated the clinical potential of the probe with 2-D circumferential PA and OCT imaging, and with multispectral PA imaging.

AB - Intravascular imaging in percutaneous coronary interventions can be an invaluable tool in the treatment of coronary artery disease. It is of significant interest to provide molecular imaging contrast that is complementary to structural contrast provided by optical coherence tomography (OCT) and intravascular ultrasound imaging (IVUS). In this study, we developed a dual-modality intravascular imaging probe comprising a commercial OCT catheter and a high sensitivity fiber optic ultrasound sensor, to provide both photoacoustic (PA) and OCT imaging. With PA imaging, the lateral resolution varied from 18μmto40μm; the axial resolution was consistently in the vicinity of 45 μm. We demonstrated the clinical potential of the probe with 2-D circumferential PA and OCT imaging, and with multispectral PA imaging.

KW - Endoscopic imaging

KW - Intravascular photoacoustic imaging

KW - Optical coherence tomography

KW - All-optical intravascular catheter

KW - Fiber optic ultrasound sensor

UR - https://doi.org/10.1016/j.pacs.2018.07.002

U2 - 10.1016/j.pacs.2018.07.002

DO - 10.1016/j.pacs.2018.07.002

M3 - Article

SN - 2213-5979

VL - 11

SP - 65

EP - 70

JO - Photoacoustics

JF - Photoacoustics

ER -

All-optical dual photoacoustic and optical coherence tomography intravascular probe

Abstract

UN SDGs

Keywords

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