Alternative intraoperative optical imaging modalities for fluorescence angiography in gastrointestinal surgery: spectral imaging and imaging photoplethysmography

Claire Chalopin (Lead / Corresponding author), Annekatrin Pfahl, Hannes Köhler, Luise Knospe, Marianne Maktabi, Michael Unger, Boris Jansen-Winkeln, René Thieme, Yusef Moulla, Matthias Mehdorn, Robert Sucher, Thomas Neumuth, Ines Gockel, Andreas Melzer

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)
15 Downloads (Pure)

Abstract

Introduction: Intraoperative near-infrared fluorescence angiography with indocyanine green (ICG-FA) is a well-established modality in gastrointestinal surgery. Its main drawback is the application of a fluorescent agent with possible side effects for patients. The goal of this review paper is the presentation of alternative, non-invasive optical imaging methods and their comparison with ICG-FA.

Material and methods: The principles of ICG-FA, spectral imaging, imaging photoplethysmography (iPPG), and their applications in gastrointestinal surgery are described based on selected published works.

Results: The main applications of the three modalities are the evaluation of tissue perfusion, the identification of risk structures, and tissue segmentation or classification. While the ICG-FA images are mainly evaluated visually, leading to subjective interpretations, quantitative physiological parameters and tissue segmentation are provided in spectral imaging and iPPG. The combination of ICG-FA and spectral imaging is a promising method.

Conclusions: Non-invasive spectral imaging and iPPG have shown promising results in gastrointestinal surgery. They can overcome the main drawbacks of ICG-FA, i.e. the use of contrast agents, the lack of quantitative analysis, repeatability, and a difficult standardization of the acquisition. Further technical improvements and clinical evaluations are necessary to establish them in daily clinical routine.
Original languageEnglish
Pages (from-to)222-232
Number of pages11
JournalMinimally Invasive Therapy and Allied Technologies
Volume32
Issue number5
Early online date9 Jan 2023
DOIs
Publication statusPublished - 2023

Keywords

  • Fluorescence angiography
  • indocyanine green
  • spectral imaging
  • photoplethysmography
  • real-time
  • intraoperative
  • tissue perfusion

ASJC Scopus subject areas

  • Surgery

Fingerprint

Dive into the research topics of 'Alternative intraoperative optical imaging modalities for fluorescence angiography in gastrointestinal surgery: spectral imaging and imaging photoplethysmography'. Together they form a unique fingerprint.

Cite this