Alzheimer's disease risk factor complement receptor 1 is associated with depression

TY - JOUR

T1 - Alzheimer's disease risk factor complement receptor 1 is associated with depression

AU - Hamilton, Gillian

AU - Evans, Kathryn L.

AU - MacIntyre, Donald J.

AU - Deary, Ian J.

AU - Dominiczak, Anna

AU - Smith, Blair H.

AU - Morris, Andrew D.

AU - Porteous, David J.

AU - Thomson, Pippa A.

N1 - Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2012

Y1 - 2012

N2 - Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

AB - Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

UR - https://www.scopus.com/pages/publications/84863405155

U2 - 10.1016/j.neulet.2011.12.059

DO - 10.1016/j.neulet.2011.12.059

M3 - Article

C2 - 22244847

SN - 0304-3940

VL - 510

SP - 6

EP - 9

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 1

ER -