AMPK: regulating energy balance at the cellular and whole body levels

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    162 Citations (Scopus)
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    Abstract

    AMP-activated protein kinase appears to have evolved in single-celled eukaryotes as an adenine nucleotide sensor that maintains energy homeostasis at the cellular level. However, during evolution of more complex multicellular organisms, the system has adapted to interact with hormones so that it also plays a key role in balancing energy intake and expenditure at the whole body level.
    Original languageEnglish
    Pages (from-to)99-107
    Number of pages9
    JournalPhysiology
    Volume29
    Issue number2
    DOIs
    Publication statusPublished - Mar 2014

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