An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

Pascale Gaudet, Jeffrey G. Williams, Petra Fey, Rex L. Chisholm

    Research output: Contribution to journalArticle

    28 Citations (Scopus)

    Abstract

    Background: Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information.

    Results: We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism.

    Conclusion: Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.

    Original languageEnglish
    Article number130
    Pages (from-to)-
    Number of pages12
    JournalBMC Genomics
    Volume9
    DOIs
    Publication statusPublished - 18 Mar 2008

    Keywords

    • Cellular slime mold
    • Anterior-like cells
    • Extracellular matrix
    • Macrocyst formation
    • Sexual development
    • Prestalk cells
    • Bio-ontologies
    • Surface sheath
    • Gene ontology
    • Mating types

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