An appraisal of oral retinoids in the treatment of pachyonychia congenita

TY - JOUR

T1 - An appraisal of oral retinoids in the treatment of pachyonychia congenita

AU - Gruber, Robert

AU - Edlinger, Michael

AU - Kaspar, Roger L

AU - Hansen, C David

AU - Leachman, Sancy

AU - Milstone, Leonard M

AU - Smith, Frances J D

AU - Sidoroff, Alexis

AU - Fritsch, Peter O

AU - Schmuth, Matthias

N1 - Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

PY - 2012

Y1 - 2012

N2 - Pachyonychia congenita (PC), a rare autosomal-dominant keratin disorder caused by mutations in keratin genes KRT6A/B, KRT16, or KRT17, is characterized by painful plantar keratoderma and hypertrophic nail dystrophy. Available studies assessing oral retinoid treatment for PC are limited to a few case reports.

AB - Pachyonychia congenita (PC), a rare autosomal-dominant keratin disorder caused by mutations in keratin genes KRT6A/B, KRT16, or KRT17, is characterized by painful plantar keratoderma and hypertrophic nail dystrophy. Available studies assessing oral retinoid treatment for PC are limited to a few case reports.

U2 - 10.1016/j.jaad.2011.02.003

DO - 10.1016/j.jaad.2011.02.003

M3 - Article

C2 - 21601946

SN - 1097-6787

VL - 66

SP - e193-9

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 6

ER -