An imino-linked carba-disaccharide α-D-mannosidase inhibitor

Sylvain Cottaz, John S. Brimacombe, Michael A. J. Ferguson

    Research output: Contribution to journalArticle

    21 Citations (Scopus)

    Abstract

    In connection with a project concerned with inhibition of the biosynthesis of glycosyl phophatidylinositol (GPI) anchors, we had occasion to synthesise the unsaturated (1?6)-imino-linked carba-disaccharide 2 having the `A-manno' configuration, which was also tested as a potential inhibitor of A-D-mannosidase and other glycosidases. The results of these tests and a synthesis of 2 are reported herein.
    Original languageEnglish
    Pages (from-to)341-345
    Number of pages5
    JournalCarbohydrate Research
    Volume247
    DOIs
    Publication statusPublished - 2 Sep 1993

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