In connection with a project concerned with inhibition of the biosynthesis of glycosyl phophatidylinositol (GPI) anchors, we had occasion to synthesise the unsaturated (1?6)-imino-linked carba-disaccharide 2 having the `A-manno' configuration, which was also tested as a potential inhibitor of A-D-mannosidase and other glycosidases. The results of these tests and a synthesis of 2 are reported herein.
Cottaz, S., Brimacombe, J. S., & Ferguson, M. A. J. (1993). An imino-linked carba-disaccharide α-D-mannosidase inhibitor. Carbohydrate Research, 247, 341-345. https://doi.org/10.1016/0008-6215(93)84269-C