TY - JOUR
T1 - An imino-linked carba-disaccharide α-D-mannosidase inhibitor
AU - Cottaz, Sylvain
AU - Brimacombe, John S.
AU - Ferguson, Michael A. J.
N1 - Medline is the source for the MeSH terms of this document.
PY - 1993/9/2
Y1 - 1993/9/2
N2 - In connection with a project concerned with inhibition of the biosynthesis of glycosyl phophatidylinositol (GPI) anchors, we had occasion to synthesise the unsaturated (1?6)-imino-linked carba-disaccharide 2 having the `A-manno' configuration, which was also tested as a potential inhibitor of A-D-mannosidase and other glycosidases. The results of these tests and a synthesis of 2 are reported herein.
AB - In connection with a project concerned with inhibition of the biosynthesis of glycosyl phophatidylinositol (GPI) anchors, we had occasion to synthesise the unsaturated (1?6)-imino-linked carba-disaccharide 2 having the `A-manno' configuration, which was also tested as a potential inhibitor of A-D-mannosidase and other glycosidases. The results of these tests and a synthesis of 2 are reported herein.
UR - http://www.scopus.com/inward/record.url?scp=0027906299&partnerID=8YFLogxK
U2 - 10.1016/0008-6215(93)84269-C
DO - 10.1016/0008-6215(93)84269-C
M3 - Article
AN - SCOPUS:0027906299
SN - 0008-6215
VL - 247
SP - 341
EP - 345
JO - Carbohydrate Research
JF - Carbohydrate Research
ER -