DNA polymerase d is essential for eukaryotic DNA replication and also plays a role in DNA repair. The processivity of this polymerase complex is dependent upon its interaction with the sliding clamp PCNA and the polymerase-PCNA interaction is largely mediated through the p66 polymerase subunit. We have analysed the interactions of the human p66 DNA polymerase d subunit with PCNA and with components of the DNA polymerase d complex in vivo.
Pohler, J. R. G., Otterlei, M., & Warbrick, E. (2005). An in vivo analysis of the localisation and interactions of human p66 DNA polymerase δ subunit. BMC Molecular Biology, 6(1), 17-30. https://doi.org/10.1186/1471-2199-6-17