An inexpensive microcomputer system for analysis of single channel currents

G. A. Cottrell, D. A. Duff, J. J. Lambert

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A description is given of a system for rapidly measuring the durations of open times and closed times of single channel currents obtained by patch clamp techniques. The apparatus required, a BBC microcomputer and a Unilab interface, is inexpensive and easy to use. An outline of the software is given and measurements of the accuracy of timings presented. Examples of analyses of single channel currents obtained from spinal neurones in cultures are also presented.

Original languageEnglish
Pages (from-to)259-267
Number of pages9
JournalJournal of Neuroscience Methods
Volume9
Issue number3
DOIs
Publication statusPublished - Nov 1983

Fingerprint

Microcomputers
Systems Analysis
Patch-Clamp Techniques
Software
Neurons

Keywords

  • microcomputer
  • patch
  • single channels

Cite this

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An inexpensive microcomputer system for analysis of single channel currents. / Cottrell, G. A.; Duff, D. A.; Lambert, J. J.

In: Journal of Neuroscience Methods, Vol. 9, No. 3, 11.1983, p. 259-267.

Research output: Contribution to journalArticle

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AU - Cottrell, G. A.

AU - Duff, D. A.

AU - Lambert, J. J.

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N2 - A description is given of a system for rapidly measuring the durations of open times and closed times of single channel currents obtained by patch clamp techniques. The apparatus required, a BBC microcomputer and a Unilab interface, is inexpensive and easy to use. An outline of the software is given and measurements of the accuracy of timings presented. Examples of analyses of single channel currents obtained from spinal neurones in cultures are also presented.

AB - A description is given of a system for rapidly measuring the durations of open times and closed times of single channel currents obtained by patch clamp techniques. The apparatus required, a BBC microcomputer and a Unilab interface, is inexpensive and easy to use. An outline of the software is given and measurements of the accuracy of timings presented. Examples of analyses of single channel currents obtained from spinal neurones in cultures are also presented.

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