An investigation of lower oesophageal redox potentials in gastro-oesophageal reflux patients and healthy volunteers

N Washington, R. J. C. Steele, J. W. Wright, D Bush, S L McIntosh, S Wilkinson, C Washington

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    Oesophageal electrical properties are thought to be important in the development of gastro-esophageal reflux. This study simultaneously monitored the intraoesophageal pH and redox potentials in 18 patients with gastro-oesophageal reflux symptoms and 15 asymptomatic controls, for a 24 h period. The pH and redox electrodes were positioned 5 cm proximal to the lower oesophageal sphincter, the position of which had been determined by manometry. Since significantly different behaviour was observed during the day and night, the data were divided into periods of waking and sleeping. Data were analysed for acid reflux (pH
    Original languageEnglish
    Pages (from-to)363-371
    Number of pages9
    JournalPhysiological Measurement
    Issue number4
    Publication statusPublished - 1997



    • Adult
    • Area Under Curve
    • Blood Gas Analysis
    • Electrodes
    • Esophagus
    • Female
    • Gastroesophageal Reflux
    • Humans
    • Hydrogen-Ion Concentration
    • Male
    • Manometry
    • Oxidation-Reduction
    • Reference Values

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