An overview of the cell cycle arrest protein, p21^WAF1

TY - JOUR

T1 - An overview of the cell cycle arrest protein, p21WAF1

AU - Harada, K.

AU - Ogden, G.R.

PY - 2000/1

Y1 - 2000/1

N2 - p21, also known as WAF1, Cip1, Sdi1, Mda 6 and Cap20 is a cell cycle protein that regulates and can arrest the cell cycle in G1 or S phase (either dependent or independent of p53). Its role may be pivotal in many cell processes including differentiation and apoptosis. This brief overview provides a summary of its presently known functions and indicates areas for further research, particularly in relation to oral malignant disease. Greater understanding of its role may lead to therapeutic advances in the management of malignant disease. Copyright (C) 2000 Elsevier Science Ltd.

AB - p21, also known as WAF1, Cip1, Sdi1, Mda 6 and Cap20 is a cell cycle protein that regulates and can arrest the cell cycle in G1 or S phase (either dependent or independent of p53). Its role may be pivotal in many cell processes including differentiation and apoptosis. This brief overview provides a summary of its presently known functions and indicates areas for further research, particularly in relation to oral malignant disease. Greater understanding of its role may lead to therapeutic advances in the management of malignant disease. Copyright (C) 2000 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0033991755

U2 - 10.1016/S1368-8375(99)00049-4

DO - 10.1016/S1368-8375(99)00049-4

M3 - Article

AN - SCOPUS:0033991755

SN - 1368-8375

VL - 36

SP - 3

EP - 7

JO - Oral Oncology

JF - Oral Oncology

IS - 1

ER -