An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

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• Finished

  Characterisation of Signal Transduction Pathways that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases (Programme Grant)

  Cohen, P. (Investigator)

  Medical Research Council

  1/04/13 → 31/03/18

  Project: Research

  • Ubiquitin 100%
  • Phosphorylation 68%
  • Ubiquitin Chains 64%
  • Toll-like 58%
  • Kinase 52%

• Elucidation of Molecular Mechanisms that Activate the MyD88 Signaling Network (Senior Investigator Award)

  Cohen, P. (Investigator)

  1/04/13 → 31/03/18

  Project: Research

  • Ubiquitin 100%
  • Phosphorylation 82%
  • Signaling Network 78%
  • Protein Kinase 74%
  • Toll-like 72%