Rates of cardiovascular disease are highest in the elderly. Lipid-lowering statin therapy reduces the proportional risk as effectively in older patients as in younger individuals; however, limited data are available for elderly patients with type 2 diabetes. We conducted a post hoc analysis to compare the efficacy and safety of atorvastatin among 1,129 patients aged 65-75 years at randomization with 1,709 younger patients in the Collaborative Atorvastatin Diabetes Study (CARDS).
Neil, H. A. W., DeMicco, D. A., Luo, D., Betteridge, D. J., Colhoun, H. M., Durrington, P. N., Livingstone, S. J., Fuller, J. H., Hitman, G. A., & CARDS Study Investigators (2006). Analysis of efficacy and safety in patients aged 65-75 years at randomization: Collaborative Atorvastatin Diabetes Study (CARDS). Diabetes Care, 29(11), 2378-2384. https://doi.org/10.2337/dc06-0872