Anti-malarial agents

Ian Gilbert; Neil Norcross; Beatriz Baragana; Achim Porzelle

Anti-malarial agents

Ian Gilbert (Inventor), Neil Norcross (Inventor), Beatriz Baragana (Inventor), Achim Porzelle (Inventor)

Research output: Patent

Abstract

The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

Original language	English
Patent number	PCT/GB2013/050633
IPC	C07D 215/52 (2006.01), A61K 31/4725 (2006.01), A61P 33/06 (2006.01)
Publication status	Published - 17 Oct 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

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title = "Anti-malarial agents",

abstract = "The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.",

author = "Ian Gilbert and Neil Norcross and Beatriz Baragana and Achim Porzelle",

year = "2013",

month = oct,

day = "17",

language = "English",

type = "Patent",

note = "PCT/GB2013/050633; C07D 215/52 (2006.01), A61K 31/4725 (2006.01), A61P 33/06 (2006.01) ",

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TY - PAT

T1 - Anti-malarial agents

AU - Gilbert, Ian

AU - Norcross, Neil

AU - Baragana, Beatriz

AU - Porzelle, Achim

PY - 2013/10/17

Y1 - 2013/10/17

N2 - The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

AB - The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.

M3 - Patent

M1 - PCT/GB2013/050633

ER -

Anti-malarial agents

Abstract

UN SDGs

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