The present invention relates to a novel class of quinolone-4-carboxamide Pf3D7 inhibitors of general formula (I) (Formula (I)) wherein R1, R2, R3, R4, R5, R6, R7, R8 and X are as defined herein, to their use in medicine, and in the treatment of malaria in particular, to compositions containing them, to processes for their preparation and to intermediates used in such processes.
|IPC||C07D 215/52 (2006.01), A61K 31/4725 (2006.01), A61P 33/06 (2006.01)|
|Publication status||Published - 17 Oct 2013|
Gilbert, I., Norcross, N., Baragana, B., & Porzelle, A. (2013). IPC No. C07D 215/52 (2006.01), A61K 31/4725 (2006.01), A61P 33/06 (2006.01) . Anti-malarial agents. (Patent No. PCT/GB2013/050633). http://patentscope.wipo.int/search/en/WO2013153357