Antigen traffic pathways in dendritic cells

Colin Watts, Sebastian Amigorena

    Research output: Contribution to journalArticlepeer-review

    34 Citations (Scopus)


    Dendritic cells (DC) are now believed to be the principal initiators of T cell-mediated immune responses. Their location in body tissues, migratory behaviour in response to inflammatory stimuli, endocytic properties, expression of MHC molecules and key T cell stimulatory molecules and many other attributes place these remarkable cells in a unique and influential position in the immune system. Progress in DC culture methods has recently allowed in-depth studies on the cell biological features that enable them to fulfil their crucial role in the immune response.

    Original languageEnglish
    Pages (from-to)312-317
    Number of pages6
    Issue number4
    Publication statusPublished - Apr 2000


    • Antigen presentation
    • Dendritic cells
    • Endocytosis
    • MHC

    ASJC Scopus subject areas

    • Structural Biology
    • Biochemistry
    • Molecular Biology
    • Genetics
    • Cell Biology


    Dive into the research topics of 'Antigen traffic pathways in dendritic cells'. Together they form a unique fingerprint.

    Cite this