Abstract
Dendritic cells (DC) are now believed to be the principal initiators of T cell-mediated immune responses. Their location in body tissues, migratory behaviour in response to inflammatory stimuli, endocytic properties, expression of MHC molecules and key T cell stimulatory molecules and many other attributes place these remarkable cells in a unique and influential position in the immune system. Progress in DC culture methods has recently allowed in-depth studies on the cell biological features that enable them to fulfil their crucial role in the immune response.
Original language | English |
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Pages (from-to) | 312-317 |
Number of pages | 6 |
Journal | Traffic |
Volume | 1 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2000 |
Keywords
- Antigen presentation
- Dendritic cells
- Endocytosis
- MHC
ASJC Scopus subject areas
- Structural Biology
- Biochemistry
- Molecular Biology
- Genetics
- Cell Biology