Antigen traffic pathways in dendritic cells

TY - JOUR

T1 - Antigen traffic pathways in dendritic cells

AU - Watts, Colin

AU - Amigorena, Sebastian

PY - 2000/4

Y1 - 2000/4

N2 - Dendritic cells (DC) are now believed to be the principal initiators of T cell-mediated immune responses. Their location in body tissues, migratory behaviour in response to inflammatory stimuli, endocytic properties, expression of MHC molecules and key T cell stimulatory molecules and many other attributes place these remarkable cells in a unique and influential position in the immune system. Progress in DC culture methods has recently allowed in-depth studies on the cell biological features that enable them to fulfil their crucial role in the immune response.

AB - Dendritic cells (DC) are now believed to be the principal initiators of T cell-mediated immune responses. Their location in body tissues, migratory behaviour in response to inflammatory stimuli, endocytic properties, expression of MHC molecules and key T cell stimulatory molecules and many other attributes place these remarkable cells in a unique and influential position in the immune system. Progress in DC culture methods has recently allowed in-depth studies on the cell biological features that enable them to fulfil their crucial role in the immune response.

KW - Antigen presentation

KW - Dendritic cells

KW - Endocytosis

KW - MHC

UR - https://www.scopus.com/pages/publications/0034173169

U2 - 10.1034/j.1600-0854.2000.010404.x

DO - 10.1034/j.1600-0854.2000.010404.x

M3 - Article

C2 - 11208116

AN - SCOPUS:0034173169

SN - 1398-9219

VL - 1

SP - 312

EP - 317

JO - Traffic

JF - Traffic

IS - 4

ER -