Antiphospholipid syndrome leading to paradoxical embolus and stroke via secundum atrial septal defect

Amy Campbell, Avinash Kumar Kanodia (Lead / Corresponding author), Christopher Robert Gingles, Harinath Chandrashekar

Research output: Contribution to journalArticlepeer-review

Abstract

We have presented a case of a 22-year-old man, presenting with cerebral infarct, subsequently found to have antiphospholipid syndrome (APS), deep venous thrombosis, pulmonary embolism and atrial septal defect (ASD), thereby confirming the presence of infarct due to paradoxical embolism in this patient. The importance of ASD in the patients of APS, resulting in paradoxical embolism is debatable, with recent studies undermining its importance. We have demonstrated that it does indeed happen. This would have implications in the risk assessment and management of ASD in such patients. This case report is intended to serve as a reminder of this association and the need to perform further research in this area.

Original languageEnglish
Article numbere239674
Number of pages4
JournalBMJ Case Reports
Volume14
Issue number3
Early online date16 Mar 2021
DOIs
Publication statusPublished - Mar 2021

Keywords

  • interventional cardiology
  • stroke

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