Antisperm antibodies are more prevalent in men with low sperm motility

C. L. Barratt (Lead / Corresponding author), L. M. Havelock, P. E. Harrison, I. D. Cooke

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Fifty-six men with low sperm motility (less than or equal to 40% of sperm with forward progression) who attended our infertility clinic were tested for antisperm antibodies (IgG and IgA) using the indirect immunobead test. Nineteen (34%) of these men were found to be positive (greater than 10% binding). This was significantly higher (P less than 0.01) than the incidence (5%) of antibodies in men who attended our infertility clinic with high sperm motility (greater than 40% of sperm with forward progression). It is concluded that significantly more men with low sperm motility have antisperm antibodies. The functional significance of these antibodies warrants further investigation.

Original languageEnglish
Pages (from-to)110-16
Number of pages7
JournalInternational Journal of Andrology
Volume12
Issue number2
DOIs
Publication statusPublished - 1 May 1989

Keywords

  • Autoantibodies/analysis
  • Humans
  • Infertility, Male/etiology
  • Male
  • Semen/immunology
  • Sperm Motility
  • Spermatozoa/immunology

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