Antisperm antibodies are more prevalent in men with low sperm motility

C. L. Barratt; L. M. Havelock; P. E. Harrison; I. D. Cooke

doi:10.1111/j.1365-2605.1989.tb01293.x

Antisperm antibodies are more prevalent in men with low sperm motility

C. L. Barratt (Lead / Corresponding author)
, L. M. Havelock
, P. E. Harrison
, I. D. Cooke

MED Undergraduate Medicine

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

Fifty-six men with low sperm motility (less than or equal to 40% of sperm with forward progression) who attended our infertility clinic were tested for antisperm antibodies (IgG and IgA) using the indirect immunobead test. Nineteen (34%) of these men were found to be positive (greater than 10% binding). This was significantly higher (P less than 0.01) than the incidence (5%) of antibodies in men who attended our infertility clinic with high sperm motility (greater than 40% of sperm with forward progression). It is concluded that significantly more men with low sperm motility have antisperm antibodies. The functional significance of these antibodies warrants further investigation.

Original language	English
Pages (from-to)	110-16
Number of pages	7
Journal	International Journal of Andrology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2605.1989.tb01293.x
Publication status	Published - 1 May 1989

Keywords

Autoantibodies/analysis
Humans
Infertility, Male/etiology
Male
Semen/immunology
Sperm Motility
Spermatozoa/immunology

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10.1111/j.1365-2605.1989.tb01293.x

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title = "Antisperm antibodies are more prevalent in men with low sperm motility",

abstract = "Fifty-six men with low sperm motility (less than or equal to 40\% of sperm with forward progression) who attended our infertility clinic were tested for antisperm antibodies (IgG and IgA) using the indirect immunobead test. Nineteen (34\%) of these men were found to be positive (greater than 10\% binding). This was significantly higher (P less than 0.01) than the incidence (5\%) of antibodies in men who attended our infertility clinic with high sperm motility (greater than 40\% of sperm with forward progression). It is concluded that significantly more men with low sperm motility have antisperm antibodies. The functional significance of these antibodies warrants further investigation.",

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year = "1989",

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doi = "10.1111/j.1365-2605.1989.tb01293.x",

language = "English",

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T1 - Antisperm antibodies are more prevalent in men with low sperm motility

AU - Barratt, C. L.

AU - Havelock, L. M.

AU - Harrison, P. E.

AU - Cooke, I. D.

PY - 1989/5/1

Y1 - 1989/5/1

N2 - Fifty-six men with low sperm motility (less than or equal to 40% of sperm with forward progression) who attended our infertility clinic were tested for antisperm antibodies (IgG and IgA) using the indirect immunobead test. Nineteen (34%) of these men were found to be positive (greater than 10% binding). This was significantly higher (P less than 0.01) than the incidence (5%) of antibodies in men who attended our infertility clinic with high sperm motility (greater than 40% of sperm with forward progression). It is concluded that significantly more men with low sperm motility have antisperm antibodies. The functional significance of these antibodies warrants further investigation.

AB - Fifty-six men with low sperm motility (less than or equal to 40% of sperm with forward progression) who attended our infertility clinic were tested for antisperm antibodies (IgG and IgA) using the indirect immunobead test. Nineteen (34%) of these men were found to be positive (greater than 10% binding). This was significantly higher (P less than 0.01) than the incidence (5%) of antibodies in men who attended our infertility clinic with high sperm motility (greater than 40% of sperm with forward progression). It is concluded that significantly more men with low sperm motility have antisperm antibodies. The functional significance of these antibodies warrants further investigation.

KW - Autoantibodies/analysis

KW - Humans

KW - Infertility, Male/etiology

KW - Male

KW - Semen/immunology

KW - Sperm Motility

KW - Spermatozoa/immunology

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DO - 10.1111/j.1365-2605.1989.tb01293.x

M3 - Article

C2 - 2722270

SN - 0105-6263

VL - 12

SP - 110

EP - 116

JO - International Journal of Andrology

JF - International Journal of Andrology

IS - 2

ER -

Antisperm antibodies are more prevalent in men with low sperm motility

Abstract

Keywords

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