TY - CHAP
T1 - Appendageal malignancies
AU - Harwood, Catherine A.
AU - Proby, Charlotte M.
AU - Cerio, Rino
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Appendageal tumours (ATs) are neoplasms in which differentiation occurs toward one or more adnexal structures of the skin. The increased incidence, clinicopathologic spectrum and prognosis of keratinocyte skin cancers in organ transplant recipients (OTR) have all been well documented in recent years. In contrast, there are few publications relating to post-transplant ATs. Available reports provide evidence for a probable increased incidence of at least some of these neoplasms in OTRs. However, most published studies are essentially anecdotal observations or small case series, few data are available from systematic transplant cohort studies, and there is a dearth of reliable information on the prevalence of ATs in the general population. Such factors place major limitations on attempts to accurately assess relative risk of these tumours in OTRs.
AB - Appendageal tumours (ATs) are neoplasms in which differentiation occurs toward one or more adnexal structures of the skin. The increased incidence, clinicopathologic spectrum and prognosis of keratinocyte skin cancers in organ transplant recipients (OTR) have all been well documented in recent years. In contrast, there are few publications relating to post-transplant ATs. Available reports provide evidence for a probable increased incidence of at least some of these neoplasms in OTRs. However, most published studies are essentially anecdotal observations or small case series, few data are available from systematic transplant cohort studies, and there is a dearth of reliable information on the prevalence of ATs in the general population. Such factors place major limitations on attempts to accurately assess relative risk of these tumours in OTRs.
UR - http://www.scopus.com/inward/record.url?scp=77953670863&partnerID=8YFLogxK
U2 - 10.1007/978-0-387-78574-5_29
DO - 10.1007/978-0-387-78574-5_29
M3 - Other chapter contribution
C2 - 19415216
AN - SCOPUS:77953670863
VL - 146
SP - 353
EP - 374
BT - Cancer Treatment and Research
ER -