Artificial membranes for membrane protein purification, functionality and structure studies

Mayuriben J. Parmar, Carine De Marcos Lousa, Stephen P. Muench, Adrian Goldman, Vincent L. G. Postis (Lead / Corresponding author)

Research output: Contribution to journalReview articlepeer-review

22 Citations (Scopus)


Membrane proteins represent one of the most important targets for pharmaceutical companies. Unfortunately, technical limitations have long been a major hindrance in our understanding of the function and structure of such proteins. Recent years have seen the refinement of classical approaches and the emergence of new technologies that have resulted in a significant step forward in the field of membrane protein research. This review summarizes some of the current techniques used for studying membrane proteins, with overall advantages and drawbacks for each method.
Original languageEnglish
Pages (from-to)877-882
Number of pages7
JournalBiochemical Society Transactions
Issue number3
Publication statusPublished - 9 Jun 2016


  • bicelle
  • black lipid membranes (BLM)
  • lipidic cubic phase (LCP)
  • lipodisq
  • membrane proteins
  • styrene maleic acid lipid particle system (SMALPs)
  • supported lipid bilayer (SLB)


Dive into the research topics of 'Artificial membranes for membrane protein purification, functionality and structure studies'. Together they form a unique fingerprint.

Cite this