Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles

Sinead M. Rhodes; Deborah M. Riby; Keith Matthews; David R. Coghill

doi:10.1080/13803395.2010.495057

Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles

Sinead M. Rhodes, Deborah M. Riby, Keith Matthews, David R. Coghill

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

We compared verbally matched attention-deficit/hyperactivity disorder (ADHD), Williams syndrome (WS), and typically developing individuals (N = 19 each group) on behavioral symptoms (Conners ADHD rating scale) and neuropsychological functioning. Neuropsychological tasks included those that assessed short-term memory and executive functions from the CANTAB (Cambridge Neuropsychological Test Automated Battery) neuropsychological battery. Children with WS scored within the abnormal range and did not differ in severity from ADHD children on the Conners Oppositionality, Cognitive Problems/Inattention, Hyperactivity, and ADHD Index subscales. The WS and ADHD groups also showed similar patterns of neuropsychological functioning, particularly in working memory (WM) strategy use and delayed short-term memory (STM). The findings may have clinical implications for the management of individuals with WS, highlighting the potential significance of behavioral, educational, and pharmacological strategies and treatments known to be useful in the treatment of children with ADHD for individuals with WS.

Original language	English
Pages (from-to)	147-156
Number of pages	10
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	33
Issue number	1
DOIs	https://doi.org/10.1080/13803395.2010.495057
Publication status	Published - 2011

Keywords

Executive function
Working memory
Conners Rating Scales
Attention-deficit
hyperactivity disorder
Williams syndrome
WORKING-MEMORY IMPAIRMENTS
DRUG-NAIVE BOYS
PSYCHIATRIC-DISORDERS
HYPERKINETIC DISORDER
DOWN-SYNDROME
FRONTAL-LOBE
CHILDREN
METHYLPHENIDATE
INDIVIDUALS
AUTISM

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title = "Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles",

abstract = "We compared verbally matched attention-deficit/hyperactivity disorder (ADHD), Williams syndrome (WS), and typically developing individuals (N = 19 each group) on behavioral symptoms (Conners ADHD rating scale) and neuropsychological functioning. Neuropsychological tasks included those that assessed short-term memory and executive functions from the CANTAB (Cambridge Neuropsychological Test Automated Battery) neuropsychological battery. Children with WS scored within the abnormal range and did not differ in severity from ADHD children on the Conners Oppositionality, Cognitive Problems/Inattention, Hyperactivity, and ADHD Index subscales. The WS and ADHD groups also showed similar patterns of neuropsychological functioning, particularly in working memory (WM) strategy use and delayed short-term memory (STM). The findings may have clinical implications for the management of individuals with WS, highlighting the potential significance of behavioral, educational, and pharmacological strategies and treatments known to be useful in the treatment of children with ADHD for individuals with WS.",

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author = "Rhodes, {Sinead M.} and Riby, {Deborah M.} and Keith Matthews and Coghill, {David R.}",

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AU - Coghill, David R.

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KW - HYPERKINETIC DISORDER

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KW - FRONTAL-LOBE

KW - CHILDREN

KW - METHYLPHENIDATE

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KW - AUTISM

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JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

IS - 1

ER -

Attention-deficit/hyperactivity disorder and Williams syndrome: shared behavioral and neuropsychological profiles

Abstract

Keywords

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