Attenuation of isoproterenol-mediated vasodilatation in blacks

Chim C. Lang; C. Michael Stein; R. Michael Brown; Robert Deegan; Richard Nelson; Huai B. He; Margaret Wood; Alastair J. J. Wood

doi:10.1056/NEJM199507203330304

Attenuation of isoproterenol-mediated vasodilatation in blacks

Chim C. Lang
, C. Michael Stein
, R. Michael Brown
, Robert Deegan
, Richard Nelson
, Huai B. He
, Margaret Wood
, Alastair J. J. Wood

Research output: Contribution to journal › Article › peer-review

147 Citations (Scopus)

Abstract

The mechanism of enhanced vascular reactivity in young blacks, which may play a part in the development of hypertension, has not been defined. To determine the contribution of blunted vasodilatation mediated by ß₂-adrenergic receptors to this phenomenon, we compared forearm blood-flow responses to isoproterenol in young black and white normotensive men.

Original language	English
Pages (from-to)	155-160
Number of pages	6
Journal	New England Journal of Medicine
Volume	333
Issue number	3
DOIs	https://doi.org/10.1056/NEJM199507203330304
Publication status	Published - Jul 1995

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10.1056/NEJM199507203330304

147 Citations
1 Letter

Attenuation of Isoproterenol-Mediated Vasodilatation in Blacks: response from authors.
Lang, C. C., Stein, C. M. & Wood, A. J. J., Nov 1995, In: New England Journal of Medicine. 333, p. 1503 1 p.
Research output: Contribution to journal › Letter › peer-review

5 Citations (Scopus)

Cite this

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title = "Attenuation of isoproterenol-mediated vasodilatation in blacks",

abstract = "The mechanism of enhanced vascular reactivity in young blacks, which may play a part in the development of hypertension, has not been defined. To determine the contribution of blunted vasodilatation mediated by {\ss}2-adrenergic receptors to this phenomenon, we compared forearm blood-flow responses to isoproterenol in young black and white normotensive men.",

author = "Lang, \{Chim C.\} and Stein, \{C. Michael\} and Brown, \{R. Michael\} and Robert Deegan and Richard Nelson and He, \{Huai B.\} and Margaret Wood and Wood, \{Alastair J. J.\}",

year = "1995",

month = jul,

doi = "10.1056/NEJM199507203330304",

language = "English",

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T1 - Attenuation of isoproterenol-mediated vasodilatation in blacks

AU - Lang, Chim C.

AU - Stein, C. Michael

AU - Brown, R. Michael

AU - Deegan, Robert

AU - Nelson, Richard

AU - He, Huai B.

AU - Wood, Margaret

AU - Wood, Alastair J. J.

PY - 1995/7

Y1 - 1995/7

N2 - The mechanism of enhanced vascular reactivity in young blacks, which may play a part in the development of hypertension, has not been defined. To determine the contribution of blunted vasodilatation mediated by ß2-adrenergic receptors to this phenomenon, we compared forearm blood-flow responses to isoproterenol in young black and white normotensive men.

AB - The mechanism of enhanced vascular reactivity in young blacks, which may play a part in the development of hypertension, has not been defined. To determine the contribution of blunted vasodilatation mediated by ß2-adrenergic receptors to this phenomenon, we compared forearm blood-flow responses to isoproterenol in young black and white normotensive men.

U2 - 10.1056/NEJM199507203330304

DO - 10.1056/NEJM199507203330304

M3 - Article

C2 - 7791817

SN - 0028-4793

VL - 333

SP - 155

EP - 160

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 3

ER -

Attenuation of isoproterenol-mediated vasodilatation in blacks

Abstract

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Research output

Attenuation of Isoproterenol-Mediated Vasodilatation in Blacks: response from authors.

Cite this