Abstract
Background: AVR3a is a Phytophthora infestans effector that translocates into potato cells dependent on the N-terminal RxLR leader. Results: AVR3a dimerization is inhibited by a mutation that also impairs translocation. Conclusion: Phospholipid binding of AVR3a is probably physiologically irrelevant because only denatured protein molecules bind. Significance: Our findings will help us to understand how oomycete RxLR effectors function.
Original language | English |
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Pages (from-to) | 38101-38109 |
Number of pages | 9 |
Journal | Journal of Biological Chemistry |
Volume | 287 |
Issue number | 45 |
DOIs | |
Publication status | Published - 2012 |