B-type natriuretic peptide

a simple new test to identify coronary artery disease?

A. D. Struthers, J. Davies

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    A common key question in clinical medicine is whether coronary artery disease (CAD) is present in a patient. This applies not only to patients with symptomatic chest pain, but also to those at high risk of sudden unexpected death due to asymptomatic CAD, such as diabetics. In both groups of patients, it would be of great benefit if a simple blood test could identify those most likely to have CAD. Such individuals could then be selected for more definitive but more invasive tests for CAD, such as angiography, exercise testing, etc. In addition to its established role in diagnosing heart failure, it appears that BNP may fulfil this function of pre-screening for both symptomatic and asymptomatic CAD. We review the evidence for this new prospect, which has the potential to reduce cardiac deaths by using a simple blood test to better target cardioprotective strategies to those who most need them.
    Original languageEnglish
    Pages (from-to)765-769
    Number of pages5
    JournalQJM : an International Journal of Medicine
    Volume98
    Issue number10
    DOIs
    Publication statusPublished - 2005

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    Brain Natriuretic Peptide
    Coronary Artery Disease
    Hematologic Tests
    Clinical Medicine
    Sudden Death
    Chest Pain
    Angiography
    Heart Failure
    Exercise

    Cite this

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    title = "B-type natriuretic peptide: a simple new test to identify coronary artery disease?",
    abstract = "A common key question in clinical medicine is whether coronary artery disease (CAD) is present in a patient. This applies not only to patients with symptomatic chest pain, but also to those at high risk of sudden unexpected death due to asymptomatic CAD, such as diabetics. In both groups of patients, it would be of great benefit if a simple blood test could identify those most likely to have CAD. Such individuals could then be selected for more definitive but more invasive tests for CAD, such as angiography, exercise testing, etc. In addition to its established role in diagnosing heart failure, it appears that BNP may fulfil this function of pre-screening for both symptomatic and asymptomatic CAD. We review the evidence for this new prospect, which has the potential to reduce cardiac deaths by using a simple blood test to better target cardioprotective strategies to those who most need them.",
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    B-type natriuretic peptide : a simple new test to identify coronary artery disease? / Struthers, A. D.; Davies, J.

    In: QJM : an International Journal of Medicine, Vol. 98, No. 10, 2005, p. 765-769.

    Research output: Contribution to journalArticle

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