Abstract
The following on proton pump inhibitors and chemoprevention in Barrett's esophagus includes commentaries on normalization of esophageal refluxate; the effects of 5-HT agonists on EGF secretion and of lubripristone on chloride channels agents; the role of Campylobacter toxin production; the deleterious effects of unconjugated bile acids; the role of baclofen in nonacid reflux; the threshold for adequate esophageal acid exposure; the effects of proton pump inhibitor (PPI) therapy on normalization of esophageal pH and on cell proliferation; the role of the phenotype of cellular proliferation on the effects of PPI therapy; and the value of Symptom Index and Symptom Association Probability in the evaluation of potential response to treatment. © 2011 New York Academy of Sciences.
Original language | English |
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Pages (from-to) | 93-113 |
Number of pages | 21 |
Journal | Annals of the New York Academy of Sciences |
Volume | 1232 |
Issue number | 1 |
DOIs | |
Publication status | Published - Sept 2011 |
Event | 10th OESO World Congress on Barrett's Esophagus - Boston, United States Duration: 28 Aug 2010 → 31 Aug 2010 http://www.oeso.org/pastcongresses/boston-oeso2010.html |