BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Keyphrases

• S6 Kinase 1 (S6K1) 100%
• Specific Inhibitor 100%
• Kinase Isoform 100%
• BI-D1870 100%
• Phosphorylation 60%
• AGC Kinase 60%
• Protein Kinase 40%
• Epidermal Growth Factor 40%
• Phorbol Ester 40%
• Growth Factors 20%
• High Concentration 20%
• Permeant 20%
• Mitogen-activated Protein Kinase 20%
• Protein Kinase B 20%
• Liver Kinase B1 (LKB1) 20%
• Genetic Evidence 20%
• Stress-activated Protein Kinase 20%
• Transcription Factor 20%
• CAMP Response Element-binding Protein 20%
• RSK2 20%
• Mitogen 20%
• Substrate Specificity 20%
• Glycogen Synthase kinase-3β (GSK-3β) 20%
• Small Molecules 20%
• IC50 20%
• Kidney 20%
• 293 Cells 20%
• Physiological Processes 20%
• Over 40 20%
• Phosphoryl 20%
• RSK1 20%
• Ation 20%
• Ribosomal S6 Kinase 4 (RSK4) 20%
• Individual Functions 20%

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• Ribosomal S6 Kinase 100%
• Protein Kinases 40%
• Phosphotransferase 40%
• Kinase 40%
• Epidermal Growth Factor 40%
• Agonist 40%
• Small Molecule 20%
• Growth Factor 20%
• Genetics 20%
• Cyclic Adenosine Monophosphate 20%
• Transcription Factors 20%
• Mitogen-Activated Protein Kinase 20%
• Binding Protein 20%
• Protein Kinase B 20%
• C-Jun N-Terminal Kinases 20%
• Response Element 20%
• Enzyme Specificity 20%
• IC50 20%
• Glycogen Synthase Kinase 20%
• Physiological Process 20%