Abstract
Composite materials such as ceramic are now widely used in the field of Tissue Engineering. Ceramic composites are used because of their high compressive strength, microstructure and biocompatibility. This paper describes the mechanical and biological characterisation of a commercial composite material. The material was formed into a 3D scaffold for use in cell studies using Rapid Prototyping. Secondary hardening phases (sintering and infiltration) were used in an aim to increase the compressive strength and the surface integrity of the printed samples. This resulted in increases up to 12MPa when compared with untreated samples at 4MPa. The infiltrated samples were monitored for any cytotoxic effects while in solution with Primary Tendon Fibroblasts. Both infiltration techniques resulted in early cell mortality indicating the presence of non-biocompatible substances. This research paper evaluates the mechanical properties and biocompatibility of the Rapid Prototyped material.
| Original language | English |
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| Title of host publication | World Congress on Medical Physics and Biomedical Engineering, Vol 25, Pt 10 |
| Editors | O Dossel, WC Schlegel |
| Place of Publication | New York |
| Publisher | Springer |
| Pages | 130-133 |
| Number of pages | 4 |
| ISBN (Print) | 978-3-642-03899-0 |
| Publication status | Published - 2009 |
| Event | World Congress on Medical Physics and Biomedical Engineering - Munich, Germany Duration: 7 Sept 2009 → 12 Sept 2009 http://conference.vde.com/world-congress-2009/Pages/Home.aspx |
Conference
| Conference | World Congress on Medical Physics and Biomedical Engineering |
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| Country/Territory | Germany |
| City | Munich |
| Period | 7/09/09 → 12/09/09 |
| Internet address |
Keywords
- Composites
- Rapid Prototyping
- Compressive Strength
- Cytotoxic
- infiltration