Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

T A Elhadd; T A Abdu; J Oxtoby; Gwen Kennedy; M McLaren; R Neary; J J F Belch; R N Clayton

doi:10.1210/jc.86.9.4223

Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

T A Elhadd, T A Abdu, J Oxtoby, Gwen Kennedy, M McLaren, R Neary, J J F Belch, R N Clayton

Research output: Contribution to journal › Article › peer-review

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Abstract

Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (

Original language	English
Pages (from-to)	4223-4232
Number of pages	10
Journal	Journal of Clinical Endocrinology & Metabolism
Volume	86
Issue number	9
DOIs	https://doi.org/10.1210/jc.86.9.4223
Publication status	Published - 2001

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10.1210/jc.86.9.4223

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abstract = "Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (",

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AU - Elhadd, T A

AU - Abdu, T A

AU - Oxtoby, J

AU - Kennedy, Gwen

AU - McLaren, M

AU - Neary, R

AU - Belch, J J F

AU - Clayton, R N

PY - 2001

Y1 - 2001

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AB - Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (

U2 - 10.1210/jc.86.9.4223

DO - 10.1210/jc.86.9.4223

M3 - Article

C2 - 11549653

SN - 0021-972X

VL - 86

SP - 4223

EP - 4232

JO - Journal of Clinical Endocrinology & Metabolism

JF - Journal of Clinical Endocrinology & Metabolism

IS - 9

ER -

Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

Abstract

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