Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

T A Elhadd, T A Abdu, J Oxtoby, Gwen Kennedy, M McLaren, R Neary, J J F Belch, R N Clayton

    Research output: Contribution to journalArticle

    78 Citations (Scopus)

    Abstract

    Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (
    Original languageEnglish
    Pages (from-to)4223-4232
    Number of pages10
    JournalJournal of Clinical Endocrinology & Metabolism
    Volume86
    Issue number9
    DOIs
    Publication statusPublished - 2001

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    Thrombomodulin
    Hypopituitarism
    E-Selectin
    von Willebrand Factor
    Cell Adhesion Molecules
    Biomarkers
    Intercellular Adhesion Molecule-1
    Life Expectancy
    Blood Vessels

    Cite this

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    title = "Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency",
    abstract = "Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (",
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    Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency. / Elhadd, T A; Abdu, T A; Oxtoby, J; Kennedy, Gwen; McLaren, M; Neary, R; Belch, J J F; Clayton, R N.

    In: Journal of Clinical Endocrinology & Metabolism, Vol. 86, No. 9, 2001, p. 4223-4232.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

    AU - Elhadd, T A

    AU - Abdu, T A

    AU - Oxtoby, J

    AU - Kennedy, Gwen

    AU - McLaren, M

    AU - Neary, R

    AU - Belch, J J F

    AU - Clayton, R N

    PY - 2001

    Y1 - 2001

    N2 - Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (

    AB - Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (

    U2 - 10.1210/jc.86.9.4223

    DO - 10.1210/jc.86.9.4223

    M3 - Article

    C2 - 11549653

    VL - 86

    SP - 4223

    EP - 4232

    JO - Journal of Clinical Endocrinology and Metabolism

    JF - Journal of Clinical Endocrinology and Metabolism

    SN - 0021-972X

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    ER -