Biochemical and biophysical markers of endothelial dysfunction in adults with hypopituitarism and severe GH deficiency

T A Elhadd, T A Abdu, J Oxtoby, Gwen Kennedy, M McLaren, R Neary, J J F Belch, R N Clayton

    Research output: Contribution to journalArticle

    78 Citations (Scopus)

    Abstract

    Adult hypopituitarism is known to be associated with reduced life expectancy related to excess vascular events, and endothelial dysfunction is present in patients with this condition. We studied the relationship between biophysical and biochemical markers of endothelial dysfunction, including E-selectin, intercellular cell adhesion molecule-1, von Willebrand factor, and thrombomodulin in 52 adult patients with hypopituitarism and severe GH deficiency (
    Original languageEnglish
    Pages (from-to)4223-4232
    Number of pages10
    JournalJournal of Clinical Endocrinology & Metabolism
    Volume86
    Issue number9
    DOIs
    Publication statusPublished - 2001

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