Biochemistry: The evolution of ribozyme chemistry

T. J. Wilson; D.M.J. Lilley

doi:10.1126/science.1169231

Biochemistry: The evolution of ribozyme chemistry

T. J. Wilson, D.M.J. Lilley

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Insights into the mechanisms by which ribonucleic acid enzymes catalyze reactions may help us to understand how life progressed from an early RNA world.

Original language	English
Pages (from-to)	1436-1438
Number of pages	3
Journal	Science
Volume	323
Issue number	5920
DOIs	https://doi.org/10.1126/science.1169231
Publication status	Published - 13 Mar 2009

Keywords

DELTA VIRUS RIBOZYME
ACTIVE-SITE
CRYSTAL-STRUCTURE
TRANSITION-STATE
CATALYTIC RNA
SPLICEOSOME
MECHANISM
GUANINE
INTRON
DOMAIN

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10.1126/science.1169231

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title = "Biochemistry: The evolution of ribozyme chemistry",

abstract = "Insights into the mechanisms by which ribonucleic acid enzymes catalyze reactions may help us to understand how life progressed from an early RNA world.",

keywords = "DELTA VIRUS RIBOZYME, ACTIVE-SITE, CRYSTAL-STRUCTURE, TRANSITION-STATE, CATALYTIC RNA, SPLICEOSOME, MECHANISM, GUANINE, INTRON, DOMAIN",

author = "Wilson, \{T. J.\} and D.M.J. Lilley",

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AU - Lilley, D.M.J.

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AB - Insights into the mechanisms by which ribonucleic acid enzymes catalyze reactions may help us to understand how life progressed from an early RNA world.

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KW - ACTIVE-SITE

KW - CRYSTAL-STRUCTURE

KW - TRANSITION-STATE

KW - CATALYTIC RNA

KW - SPLICEOSOME

KW - MECHANISM

KW - GUANINE

KW - INTRON

KW - DOMAIN

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U2 - 10.1126/science.1169231

DO - 10.1126/science.1169231

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SP - 1436

EP - 1438

JO - Science

JF - Science

IS - 5920

ER -

Biochemistry: The evolution of ribozyme chemistry

Abstract

Keywords

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