Biofabricated Nanostructures and Their Composites in Regenerative Medicine

TY - JOUR

T1 - Biofabricated Nanostructures and Their Composites in Regenerative Medicine

AU - Makvandi, Pooyan

AU - Ghomi, Matineh

AU - Padil, Vinod V.T.

AU - Shalchy, Faezeh

AU - Ashrafizadeh, Milad

AU - Askarinejad, Sina

AU - Pourreza, Nahid

AU - Zarrabi, Ali

AU - Nazarzadeh Zare, Ehsan

AU - Kooti, Mohamad

AU - Mokhtari, Babak

AU - Borzacchiello, Assunta

AU - Tay, Franklin R.

PY - 2020/7/24

Y1 - 2020/7/24

N2 - Biosynthesis of nanomaterials is gaining attention as a sustainable, environmentally friendly, and reliable method for manufacturing a extensive array of nanostructures, such as metal/metal oxides and organic and hybrid materials. Green synthesis is considered a crucial tool to reduce the harsh effects associated with conventional synthesis. Nanocomposite materials containing biosynthesized nanostructures are highly sought after in regenerative medicine. In the present Review, biosynthesis of metal/metal oxides and carbon-based nanomaterials using microorganisms (e.g., bacteria and fungi) and natural compounds (e.g., polysaccharides, proteins, fruit juices, and plant extracts) is highlighted. The toxicity of biosynthesized nanoparticles for biomedical application is also reviewed in depth. The applications of bionanocomposites prepared from these ecofriendly nanoparticles in tissue engineering are reviewed to provide readers with a background for future studies.

AB - Biosynthesis of nanomaterials is gaining attention as a sustainable, environmentally friendly, and reliable method for manufacturing a extensive array of nanostructures, such as metal/metal oxides and organic and hybrid materials. Green synthesis is considered a crucial tool to reduce the harsh effects associated with conventional synthesis. Nanocomposite materials containing biosynthesized nanostructures are highly sought after in regenerative medicine. In the present Review, biosynthesis of metal/metal oxides and carbon-based nanomaterials using microorganisms (e.g., bacteria and fungi) and natural compounds (e.g., polysaccharides, proteins, fruit juices, and plant extracts) is highlighted. The toxicity of biosynthesized nanoparticles for biomedical application is also reviewed in depth. The applications of bionanocomposites prepared from these ecofriendly nanoparticles in tissue engineering are reviewed to provide readers with a background for future studies.

KW - Ions

KW - Metal nanoparticles

KW - Metal oxide nanoparticles

KW - Metals

KW - Nanoparticles

UR - https://www.scopus.com/pages/publications/85088634427

U2 - 10.1021/acsanm.0c01164

DO - 10.1021/acsanm.0c01164

M3 - Article

SN - 2574-0970

VL - 3

SP - 6210

EP - 6238

JO - ACS Applied Nano Materials

JF - ACS Applied Nano Materials

IS - 7

ER -