Biofilm formation by Bacillus subtilis: new insights into regulatory strategies and assembly mechanisms

Lynne S. Cairns, Laura Hobley, Nicola R. Stanley-Wall (Lead / Corresponding author)

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    106 Citations (Scopus)
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    Biofilm formation is a social behaviour that generates favourable conditions for sustained survival in the natural environment. For the Gram-positive bacterium Bacillus subtilis the process involves the differentiation of cell fate within an isogenic population and the production of communal goods that form the biofilm matrix. Here we review recent progress in understanding the regulatory pathways that control biofilm formation and highlight developments in understanding the composition, function and structure of the biofilm matrix.

    Original languageEnglish
    Pages (from-to)587-598
    Number of pages12
    JournalMolecular Microbiology
    Issue number4
    Early online date18 Jul 2014
    Publication statusPublished - Aug 2014


    • Bacillus subtilis
    • biofilm
    • MATRIX
    • assembly
    • hydrophobin

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